A highly efficient synthesis of biologically active spirooxindole derivatives with MoO3 as a mild catalyst under solvent-free conditions
عنوان مقاله: A highly efficient synthesis of biologically active spirooxindole derivatives with MoO3 as a mild catalyst under solvent-free conditions
شناسه ملی مقاله: ICMRS01_121
منتشر شده در کنفرانس بین المللی یافته های نوین پژوهشی در علوم،مهندسی و فناوری با محوریت پژوھشھای نیاز محور در سال 1394
شناسه ملی مقاله: ICMRS01_121
منتشر شده در کنفرانس بین المللی یافته های نوین پژوهشی در علوم،مهندسی و فناوری با محوریت پژوھشھای نیاز محور در سال 1394
مشخصات نویسندگان مقاله:
Farzaneh Mohamadpour - Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box 98135-674 Zahedan, Iran
Malek Taher Maghsoodlou
Reza Heydari
خلاصه مقاله:
Farzaneh Mohamadpour - Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box 98135-674 Zahedan, Iran
Malek Taher Maghsoodlou
Reza Heydari
MoO3 as an environmentally benign nature catalyst for the multi-component efficient synthesis of biologically spirooxindole derivatives is studied. And we studied three-component, one-pot condensation of isatin/acenaphthequinone, malononitrile and different reagents including 1, 3-dicrbonyl compounds, naphthol and 4-hydroxycumarin under thermal and solvent-free conditions in the presence of MoO3 as a mild catalyst. solvent-free conditions, short reaction times, good yields, non-toxic, in expensive, simple operational procedures, one-pot, mild, easily separated from the reaction mixture with no column chromatographic separation for the economical synthesis of these fused biologically compounds are the major advantages of this literature.
کلمات کلیدی: MoO3, Spirooxindole derivatives, Multi-component reactions, Solvent-free conditions
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/519527/