Mansoureh Mirrashid - Department of Electrical Engineering, Aliabad Katoul Branch, Islamic Azad University, Aliabad Katoul, Iran
Hamed Hosseini - Department of Mechanical Engineering, Aliabad Katoul Branch, Islamic Azad University, Aliabad Katoul, Iran
Alireza Maghsoudlou - Department of Electrical Engineering, Aliabad Katoul Branch, Islamic Azad University, Aliabad Katoul, Iran

Pursuit of a closed-loop artificial pancreas that automatically controls the blood glucose of individuals with diabetes has intensified during the past 6 years. Continuous insulin infusion pumps have been widely available for over two decades, but ‘‘smart pump’’ technology has made the devices easier to use and more powerful. Continuous glucose monitoring (CGM) technology has improved and the devices are more widely available. A number of approaches are currently under study for fully closed-loop systems; most manipulate only insulin, while others manipulate insulin and glucagon. In this paper, an overview of some MPC algorithms which aim to close the loop for blood glucose control in diabetic patients is given.

Diabetes mellitus, artificial pancreas, glucose control, model predictive control (MPC)