The Relationship between the Presence of Enterotoxin Type B Gene and Antibiotic Resistance in Staphylococcus aureus

Staphylococcus aureus is a hazard to human health since they can cause a wide variety of hospital-associated infections ranging from minor skin infections topost-operative wound infections and food poisoning which produces many different virulence factors, including enterotoxins (SEs). Although studies have been doneregarding the difference between virulence factors of sensitive strains and resistant to antibiotics, the aim of this study was to investigate this topic indifferent patients. This cross-sectional study was performed on 100 patients admitted to a hospital in Tehran. After preparing of wounds samples, antibiogramstudy was done by disc diffusion method and prevalence of staphylococcal enterotoxin type B or seb gene was confirmed by Polymerase Chain Reaction. Datawas analyzed using SPSS 17 software. Results showed that the highest percentage of isolates with positive seb gene is about 7% which related to amoxicillin (6.6%), penicilline and cotrimoxazole (6.5%). More than 90% of isolate are resistant toamoxicillin, penicillin and cotrimoxazol. According to results, a significant relationship between seb gene and resistance to related antibiotics was not observed.

Keywords:

Antibiotic Resistance , Enterotoxin B Gene , Relationship , Staphyloccus aureus