Surface modification and functionalization for dopamine and ascorbic acid detection

Dopamine (DA) is a monoamine neurotransmitter found in brain and is essential for the normal functions of the central nervous system and plays a significant role in the function of humanmetabolism. It is important to develop sensitive sensor for the determination of dopamine by decreasing the interference of ascorbic acid [1, 2]. In this study, zinc oxide/polyvinyl alcoholnanostructured hybrid film were prepared by electrochemical deposition method on the F-doped SnO2 conductive glass (FTO/ZnO/PVA). Zinc oxide (ZnO) has been recently used as transducer for fabrication of sensors due to its unique ability to promote electron transfer, non-toxicity, biological compatibility, enhanced analytical performance, easy manufacture and low cost [3-5].PVA selection criteria was based on its water solubility and controlling the growth and crystallization of ZnO by tuning PVA content in electrodeposition bath.[6] Surface of the ZnO– polymer hybrid films were characterized by field emission-scanning electron microscopy (FESEM).Monitoring of sensor fabrication was performed using cyclic voltammetry (CV). The fabricated sensor was used to determine dopamine by differential pulse voltammetry technique.

Keywords:

Thin film , Dopamine sensor , Electrodeposition , Zinc oxide