A New potentiometric Sensor for Determination of Vitamin B6 Based on Nano silver Modified Carbon Paste Electrode

This research introduces design and construction of a nano composite carbon paste electrode for fast and simple determination of Vitamin B6 in pharmaceutical formulation. A potentiometricsensor for Vitamin B6 (VB6) based on carbon paste electrode modified by silver nanoparticles were prepared and fully characterized in terms of composition, usable pH range. This electrode illustrated fast, stable and Nernstian response over a relatively wide concentration range of 1×10-6 -1×10-2 M with a detection limit of 4.84×10-7 M was obtained for vitamin B6. Validation of the method shows suitability of the sensors for application in quality control analysis of drug in pharmaceutical formulation

Keywords:

potentiometric , Carbon Paste Electrode , Vitamin B6 , Nano silver