Ebrahim Kianmehr - School of Chemistry, College of Science, University of Tehran, Tehran, Iran
Yousef Amiri Lomedasht - School of Chemistry, College of Science, University of Tehran, Tehran, Iran
Nasser Faghih - School of Chemistry, College of Science, University of Tehran, Tehran, Iran

Aryl pyridine derivatives are important building blocks in organic synthesis.[1] They have found widespread application in natural products, herbicides, surfactants, insecticides, pharmaceuticals and biologically active compounds.[2] The C–N bond forming reactions through C-H functionalization have emerged as one of the most important strategy in synthetic chemistry due to elimination of prefunctionalization step of the coupling partners.[3] In recent years, much attention has been paid to transition metals as C-H bond activating agents. Using inexpensive transition metals such as copper, as an activating agent for C-H bond activation, is economically of great importance. The use of cyanate salts as a coupling partner to form C-N bond have been reported rarely.in this work, the heteroarylated acetanilide derivatives are prepared from 2-arylpyridines in the presence of copper salts. By this protocol, various heteroarylated acetanilide derivatives are synthesized in good yields. 2-phenylpyridines containing electron-donating and electron-withdrawing groups are supposed to be well tolerated by this transformation