Hassan Farhadnejad - Students’ Research Committee, Department of Pharmaceutics and Pharmaceutical Nanotechnology,School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Seyed Alireza Mortazavi - Department of Pharmaceutics and Pharmaceutical Nanotechnology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Mohammad Erfan - Department of Pharmaceutics and Pharmaceutical Nanotechnology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Zhila ZareAkbari - High school teacher of 5 zone of Tabriz, ministry of education, Tabriz, Iran

In the present project, pH sensitive sodium alginate beads were proposed as a protective capsule for montmorillonite-propranolol (MMT-PPN) nanohybrids in simulated gastrointestinal conditions. The studies of in-vitro PPN release showed a better protection in simulated gastric conditions and a controlled release in the simulated intestinal conditions for alginate-encapsulated MMT-PPN nanohybrids.

propranolol, nanohybrid, montmorillonite, sodium alginate, nanocomposite