Spontaneous Interfacial Formation of Pluronic Layer, Part 2: Membrane Efficiency

Variable micellar forms of pluronics are applicable in a wide range of issues. The behavior of block copolymers containing hydrophilic and hydrophobic blocks of poly ethylene oxide (PEO) and poly propylene oxide (PPO), respectively was studied in immiscible phase of aqueous/organic solvents. Mucus-like, naked eye visible white layer consisting of pluronic P123 micelles was observed between organic/aqueous phases. Pluronic P123 tends to migrate from aqueous phase to organic one through the white membrane. Weibull, Peppas and modified Korsmeyer–Peppas models were applied to study the kinetic of permeability and release behavior. Results showed the efficiency of membrane in controlled diffusion of P123 chains into water