XPS study of modified Polydimethylsiloxane with 3-aminopropyltriethoxysilane nanolayer used in Biomedical Applications

PDMS (Polydimethylsiloxane) is important in such biomedical applications due to their oxygen permeability, low toxicity and biocompatibility. However, the surface of pristine PDMS is unsuitable for the adhesion of cells and the adsorption of extracellular matrix (ECM) proteins, because of its high hydrophobicity. To avoid these drawbacks, several attempts have been done to modify the surface of PDMS such as oxygen plasma. In this study the surfaces of PDMS polymers were modified by firstly creation of temporary hydroxyl groups after exposure the polymers to the diluted acidic oxygen peroxide solution and then covalently bonding of amino group via incubation in a (3-aminopropyl) trimethoxysilane (APTES) solution, both in the room temperature. The formation of amino groups was characterized by X-ray photoelectron spectroscopy (XPS). The results clearly show that amino groups nano layer formed on the surface of PDMS surface improved

Keywords:

PDMS , biomedical , biocompatibility , biocompatibility , wettability