CuI nanoparticles on modified poly(styrene-co-maleic anhydride): an efficient catalyst for the synthesis of Hantzsch 1,4-dihydropyridines

In this work, CuI nanoparticles on modified poly(styrene-co-maleic anhydride) is utilized as a highly efficient, heterogeneous and recyclable catalyst for the preparation of biologically active substituted Hantzsch 1,4-dihydropyridine via one-pot multi-component condensation of aromatic aldehydes, 1,3-dicarbonyls and ammonium acetate under solvent-free conditions. This catalyst can be recycled without pre-activation and reloaded up to 3 consecutive runs without significant decrease in its efficiency

Keywords:

Polymer-supported catalyst - Poly(styrene-co-maleic anhydride) - Hantzsch reaction -Copper nanoparticles - 1 , 4-dihydropyridines