Combination of electrospun nanofibers and Coral micro particles to improve mechanical properties as well as the porosity and pore size of the resultant scaffold

To design an ideal scaffold, various factors should be considered, such as pore size and morphology, mechanical properties versus porosity, surface properties and appropriate biodegradability. Of these factors, the importance of mechanical properties on cell growth is particularly obvious in tissues such as bone, cartilage, blood vessels, tendons and muscles. Although electrospun nanofibers provide easily applicable nano-sized structures which could beused as biomedical scaffolds, the mechanical properties are poor since an increased pore size and porosity are generally accompanied by a decrease in mechanical properties. In this study, PCL scaffolds containing coral micro particles were prepared and effect of these particles on pore size and mechanical properties of the scaffolds investigated

Keywords:

electrospinning , pore size , compression modulus , coral , PCL