Ezzatollah Fathi - Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran
Shahram Jamshidi - Depart ment of Internal Medicine, University of Tehran, Small Animal Hospital of Veterinary Faculty, Tehran,Iran

The aim of the present case report is to describe the outcome, hematological and biochemical changes of treatment of idiopathic thrombocytopenia in a Terrier dog using human intravenous immunglobulin. The complete blood count, serum biochemistry, indirect immunofluorescence antibody and direct coomb’s tests, radiography and sonography were performed. Laboratory findings indicated sever thrombocytopenia (<15×103/μl) and mild leukocytosis. Increase in the erythrocyte sedimentation rate and total protein concentration were last up to 19 and 14 days, respectively .After it, areduction was observed and no relapse was reported. This case report provides the first successful treatment and clinical evidence of a terrier dog with idiopathic thrombocytopenia in which no underlying etiology has been identified. It was concluded that human intravenous immunoglobulin infusion (1 g/kg) is a safe treatment with a significant increase in platelet count without increase in hospitalization and the cost of patient care

dog, idiopathic thrombocytopenia, treatment, human intravenous immunoglobulin