Sharmin Irani - Chemistry Department, The University of Sistan and Baluchestan, P. O. Box ۹۸۱۳۵-۶۷۴, Zahedan, Iran.
Malek Taher Maghsoodlou - Chemistry Department, The University of Sistan and Baluchestan, P. O. Box ۹۸۱۳۵-۶۷۴, Zahedan, Iran.

An efficient and simple protocol for the one-pot three-component synthesis of 3,4-dihydropyrano[3,2-c]chromenes (4) is described, via the reaction of aromatic aldehydes (1), malononitril (2) and 4-hydroxycumarin (3) in the presence of 10 mol% of piperazine as catalyst, in ethanol (EtOH) at ambient temperature. Short reaction times, environmentally friendly procedure and excellent yields are the main advantages of this procedure, which makes it more economical than other environment-friendly methods.

3,4-dihydropyrano[3,2-c]chromenes, piperazine , ambient temperature