SYNTHUR SIS (0FFLUORAPATTE-FORSTER TE NAN.000MUP0SITE SCAFFOLDS VTA GELCASTING METHOD FORBONE TISSUE ENGINEERING

In bioengineering, there is a desire to create three-dimensional porous ceramic structures for a variety of applications. This porosity is desired to allow for tissue in-growth and fluid transport. However, inadequate mechanical properties of ceramic scaffolds have limited its application. Recently, a ceramic processing technology known as gel casting has been used to create parts with complex geometries. In this study the fluorapatite-30 percent of weight forsterite nanocomposite powder were fabricated by sol-gel method and after the gel-casting process, heat treatment was carried out in various temperatures for calcinations and separation of polymers .The pore morphology size and distribution of the resulting scaffolds were characterized using a scanning electron microscope. X-ray diffraction was used to determine the crystal structure and chemical composition of scaffolds. Besides, porosity was investigated by using Archimedes method. The results showed successful fabrication of composite scaffold with porosity in the range of 65-87 percent and grain size in the range 35-65 nm and pore size between 100-150 microns. The mechanical properties of the scaffold show it can be a suitable candidate for use in bone tissue engineering applications.

Keywords:

fluorapatite , forsterite , scaffolds , gel casting , bone tissue engineering