Mahboobeh Shirazi - Department of Obstetrics and Gynecology, Women’s Hospital, Tehran University of Medical Sciences, Tehran, Iran
Mona Mohseni - Department of Obstetrics and Gynecology, Women’s Hospital, Tehran University of Medical Sciences, Tehran, Iran
Mahsa Ghajarzadeh - Brain and Spinal Injury Research Center, Tehran University of Medical Sciences, Tehran, Iran

Background: Chorionic villus sampling (CVS) and amniocentesis are two invasive methods of diagnosticapproaches for prenatal diagnosis. The indication, adverse effects and final outcome of these two methods aredifferent. The goal of this study was to compare indication, complications and outcomes of CVS andamniocentesis in pregnant women underwent prenatal screening program.Methods: Medical records of 1464 women who underwent CVS, or amniocentesis were reviewed in twotertiary hospitals (imam and women hospitals, affiliated hospitals of Tehran University of Medical Sciences).Results: For 1073 patients amniocentesis was performed while for 391 cases CVS was one. Mean maternalage, gestational age, and age at birth of the neonates were significantly lower in CVS group than the othergroup. Mean needle time was significantly higher in CVS group. Mean needle time was significantly higher inCVS Group (1.3 vs. 1.5, P < 0.001). The most finding of CVS result was minor Thalassemia while trisomy 21was the most finding in amniocentesis group. Rupture of membranes was the most side effects inamniocentesis group and intrauterine fetal death was the most complication in CVS group.Conclusions: Indication, results and complications of CVS and amniocentesis are different.© 2015 Tehran University of Medical Sciences. All rights reserved.Citation: Shirazi M, Mohseni M, Ghajarzadeh M. Complications, Indications and Results of TwoScreening Methods: Amniocentesis and Chorionic Villus Sampling. Acad J Surg, 2015; 2(1-2): 23-6.

Amniocentesis, Chorionic villi sampling, Pregnant women, Prenatal diagnosis, Indication,Complications