Mojtaba Javaherzadeh - Associate Professor, Department of Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Ali Shekarchizadeh - Researcher, Poursina Hakim Gastrointestinal (GI) Research Center, Poursina Hakim Research Institution, Isfahan, Iran
Babak Sabet - Assistant Professor, Department of Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Seyed Ali Mousavi-Almaleki - Surgeon, Department of Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Background: This study aimed to assess the prevalence of Helicobacter pylori infection in gastric andgallbladder in patients with acute cholecystitis or symptomatic cholelitiasis undergoing cholecystectomy.Methods: 43 patients with biliary disease (cholecystitis or cholelitiasis) with inclusion criteria were selected inShahid Modarres Hospital, Tehran, Iran. The data including age, sex, and the presence of Helicobacter pylori inbiopsy samples of gallbladder and gastric mucosa for each patient were recorded and analyzed using SPSS software.Results: The biopsy specimens of gastric and gallbladder mucosa of 43 patients with the mean age of54.8 ± 9.9 years were studied. 22 (51.2%) patients had acute cholecystitis and 21 (48.8%) had cholelithiasis.Among the gastric samples, 14 patients (32.6%) (9 men and 5 women) and in the gallbladder samples, 19patients (44.2%) (8 women and 11 men) were positive for Helicobacter pylori. The simultaneous presence ofHelicobacter pylori in the gastric and gallbladder mucosa was seen in 6 patients (13.9%). 10 patients (23.2%)were smokers, and 33 (76.7%) were non-smokers.Conclusions: It can be said that the presence of Helicobacter pylori in gallbladder can play an important role inthe creation and spread of the infection. But the simultaneous presence of Helicobacter pylori infection ingastric and gallbladder cannot be a good standard to evaluate the diseases of the bile ducts.© 2014 Tehran University of Medical Sciences. All rights reserved.Citation: Javaherzadeh M, Shekarchizadeh A, Sabet B, Mousavi-Almaleki SA, Mirafsharieh A.Simultaneous Helicobacter Pylori Infection in Gastric Mucosa and Gallbladder Mucosa in Patients withCholecystitis; Is There Any Relationship Acad J Surg, 2016; 3(1-2): 12-4.

Acute cholecystitis; Cholelithiasis; Helicobacter pylori