A Tandem Oxidation-Aldol Condensation Sequence for the Synthesis of Bis(arylmethylidene)cycloalkanones by Nanostructured MnO2

A novel one-pot synthesis of bisarylmethylidenes of cyclic ketones is developed starting from their corresponding alcohol substrates. Reactions take place efficiently at room-temperature under catalysis of MgBr2.OEt2 by using nanostructured MnO2 and Et2NH.

Keywords:

Tandem oxidation , nanostructured MnO2 , bisarylmethylidenes , aldol condensation