Morteza Zarei Hajiabadi - Department of Chemistry, pnu University, minab Branch, minab, Iran
Sima Poorghasem - Department of Chemistry, pnu University, minab Branch, minab, Iran
Mahsa Salehi - Department of Chemistry, pnu University, minab Branch, minab, Iran

A very quick, effective and environmentally moderate process for the combination of new spiro derivatives is desc. These compounds were prepared through domino one-pot and multicomponent condensation reactions of ninhydrin, orthophenydiamine, dialkyl acetylenedicarboxylate and alkyl or aryl isocyanides when there is a as catalyst. Prominent among the advantages of this work is simplework up procedure, good to high product yields with high purity and short reaction times.

Multi-component reaction, Spiro compounds, Isocyanide, Ionic liquids