Shakiba Shahbazi - Department of Microbiology, Qom Branch, Islamic Azad University, Qom, I. R.Iran,
Mohammad Reza Zolfaghari - Department of Microbiology, Qom Branch, Islamic Azad University, Qom, I. R. Iran,
Mohammad Ali Ghasemzadeh - Department of Chemistry, Qom Branch, Islamic Azad University, Qom, I. R. Iran,

In this research a series of pyranopyrazoles were efficiently synthesized via the one-pot fourcomponent reactions of ethyl acetoacetate, hydrazinehydrate, aldehydes and malononitrile in the presence of Co3O4@SiO2-NH2 nanocomposites ascatalyst. This study offers many advantages including short reaction times, excellent yields, environmental friendly nature, simple purification techniques and economic availability of the catalyst. The structure andmagnetic characteristics of the nanocatalyst were fully characterized by spectral techniques including TEM, FE-SEM, EDX, XRD, FT-IR and VSM analysis.

Multi-component ،1,4- dihydropyrano[2,3-c]pyrazoles، Co3O4@SiO2-NH2 nonocomposites