Copula andW.L.Wapproaches for composite end point of multivariate failure time

Copula models offer an alternative approach for modeling association between failure time. In this article two types of copula is considered: Clayton copula and Frank copula. Another approach is the marginal approach of Wei, Lin, Weissfeld (WLW) for handling multivariate failure time data.

Keywords:

multivariate failure time data , Clayton copula , Frank copula , Composite End Point (CEP) , terminal , clinical trials