azita faramarzi - Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Department of Anatomical Sciences and Biology, Faculty ofMedicine, Kermanshah University of Medical Sciences, Ke
Mohammad Ali Khalili - Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Giulietta Micara - Department of Obstetrics and Gynecology, UOC OGC۰۳ Infertility and IVF University of Rome La Sapienza, Viale Regina Elena ۳۲۴-۰۰۱۶۱ Rome
Azam Agha Rahimi - Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

High implantation success following in vitro fertilization cycles are achieved via the transfer of embryos with the highest developmental competence. Multiple pregnancies as a result of the transfer of several embryos per cycle accompany withvarious complication. Thus, single-embryo transfer (SET) is the preferred practice in assisted reproductive technique (ART) treatment. In order to improve the pregnancyrate for SET, embryologists need reliable biomarkers to aid their selection ofembryos with the highest developmental potential. Time-lapse technology is a noninvasive alternative conventional microscopic assessment. It providesuninterrupted and continues the survey of embryo development to transfer day. Today, there are four time-lapse systems that are commercially available for ART centers. In world and Iran, the first time lapse babies were born in 2010 and 2015,respectively, conceived by SET. Here, we review the use of time-lapse monitoring in the observation of embryogenesis as well as its role in SET. Although, the findingsfrom our review support common use of time-lapse monitoring in ART centers; but, future large studies assessing this system in well-designed trials are necessary.

Embryo selection, Kinetic, Assisted reproductive technology, Time-lapse