Taraneh Ehteshamzadeh - Polymer engineering group, Faculty of technology and engineering, Golestan University, Gorgan, Iran
Mehdi Ghaffari - Polymer engineering group, Faculty of technology and engineering, Golestan University, Gorgan, Iran
Saeed Kakaei - NSTRI, Nuclear Fuel Cycle Research Institute, P.O. Box ۱۱۳۶۵/۸۴۸۶, Tehran, Iran
Ali Reza Khanchi - NSTRI, Nuclear Fuel Cycle Research Institute, P.O. Box ۱۱۳۶۵/۸۴۸۶, Tehran, Iran

Magnetic drug delivery systems can be used in cancer treatment. In this study, magnetic nanocomposite hydrogels have been developed and demonstrated to be responsive to alternating magnetic fields. Fe3O4 nanoparticles were synthesized by co-precipitation method. The synthesized nanoparticles are modified by (3-aminopropyl)triethoxysilane (APTES) and coated with polyvinylpyrrolidone (PVP). Modified nanoparticles characterized by FTIR, SEM, XRD and magnetic properties are determined by vibrating sample magnetometer (VSM). The results indicate that PVP coated iron oxide nanoparticles are promising for magnetically targeted drug delivery

Fe3O4; drug delivery; hydrogel; polyvinylpyrrolidone