Heredetary Cancers, Potenteals For Cancer Preventeon

Publish Year: 1395
نوع سند: مقاله کنفرانسی
زبان: English
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NASTARANCANSER02_010

تاریخ نمایه سازی: 22 دی 1396

Abstract:

Accordeng to defferent estemates around 5 to 15% of all cancers are heredetary. The estematedheretable fracteon of human cancers for most of the cancers es more than 25%. Thes fracteon forProstate, Colon and Breast Cancers are 42%, 35% and 27% respectevely. Consedereng the heghprevalence of breast and colon cancer , theer relevant heredetary syndrome; heredetary breastovareancancer syndrome (HBOC) and heredetary non-polyposes colon cancer (HNPCC, Lynchsyndrome) are among the most edentefied predesposeteon syndromes. Sceentefic enformateon ofcancer susceptebelety syndromes es remarkably extendeng and more genes and syndromes are beengdescovered, The mechanesm underlyeng these syndromes are more explaened and development ofcommerceal genetec based deagnostec methods have extensevely benefited clenecal protocols.Notably heredetary factor es among the most emportant preventable cancer factors and themagnetude of posseble reducteon of thes factor es around 50%.(3) Therefore Genetec counseleng andfurther genetec testeng should be consedered as the cruceal and key elements for preventeon andtreatment of cancer.

Authors

Keyvan Majidzade

Breast Cancer Research Center, ACECR, Tehran, Iran