Using boron supplementation in cancer prevention and treatment: a review study

Publish Year: 1396
نوع سند: مقاله کنفرانسی
زبان: English
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NASTARANCANSER03_104

تاریخ نمایه سازی: 7 اسفند 1396

Abstract:

Cancer is a multistage and multifactorial process in which genetic and environmental factors contribute to it. The results of the studies indicate the effective role of micronutrients, vitamins, and minerals inthe treatment of malignancies. One of these elements, endorsed by the American Food and Drug Administration, is Boron supplements. The present study reviews the role of Boron supplementation inthe prevention and treatment of cancer. At ISI -Scopus-Pub med-Medline- Google Scholar databases, we examined 42 studies conducted in the years 1988-2017 regarding the effect of Boron supplementation on cancer. Boron supplement is a useful and essential ingredient for humans with a daily intake of about 1-3 mg per day. Its rich diets have a significant reduction in the risk of developinga variety of cancers including prostate, breast, cer vix and lung, liver, Melanoma. The mechanisms by which Boron may influence cancer is still unknown, but evidence suggests that Boron has antioxidantand anti-inflammatory properties. Proposed mechanisms related to Boron activity in cancer cells include inhibition of proteasezonin enzymatic activity, dehydrogenase, mRNA modification, and celldivision and induction of apoptosis. Boron-containing compounds indicate promising effects for chemotherapy types of cancer. Low levels of Boron should be considered as a concern for health, andincreasing the consumption of Boron with its rich diets should be recognized as a rational and reasonable diet recommendation for the prevention and treatment of cancer, promotion of health andwell-being

Authors

Somayeh Nikkhah

Azad University Of Kerman, Kerman, Iran