Simindokht Shoaei - Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
Shahnaz Sali - Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
Hooman Yousefi - Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran

Background: Nosocomial infections have high mortality rates because of infective organisms specific characteristics and the type of patients identified with different comorbid diseases. The aim of this study was to determine the prevalence rate of different microorganisms and their characteristics in terms of resistance to various antibiotics.Materials and Methods: Samples of urine, blood, abscess and wound secretion, and septum or tracheal secretions were cultured for 139 patients who were hospitalized during September 2012 to September 2014 and identified with nosocomial infection in different hospital wards. Then the type of microorganism and their antibiotic resistance were determined for each patient using culture antibiogram with disk diffusion method. Results were then analyzed using SPSS software.Results: The incidence of nosocomial infections was observed more in men than in women. Fever and purulent discharge from the wound site were the most common symptoms, leading to patient s hospitalization. Most patients were from the transplant and urology wards. Urinary tract, skin, and soft tissue infections (SSTI) had the highest prevalence rate in patients. Escherichia coli was the most common infectious microorganism in patients, which was sensitive to imipenem and meropenem. Klebsiella as the next most common infectious microorganism was resistant to imipenem.Conclusion: The results of this study are consistent with the previous studies. Due to infectious microorganisms resistance to antibiotics, it is recommended to reduce the consumption of antibiotics.

Nosocomial infection, Antimicrobial resistance, Prevalence, Infection control