Green Manufacturing of β-Lactam Antibiotic ‘Cephalexin’ with Immobilized Penicillin-G Acylase
عنوان مقاله: Green Manufacturing of β-Lactam Antibiotic ‘Cephalexin’ with Immobilized Penicillin-G Acylase
شناسه ملی مقاله: DSCONF04_278
منتشر شده در چهارمین کنفرانس بین المللی یافته های نوین علوم و تکنولوژی در سال 1396
شناسه ملی مقاله: DSCONF04_278
منتشر شده در چهارمین کنفرانس بین المللی یافته های نوین علوم و تکنولوژی در سال 1396
مشخصات نویسندگان مقاله:
Babak Pourrostam - Antibiotic Sazi Iran Company
Faramarz Asghari - Antibiotic Sazi Iran Company
Marzieh sadatshahabi - Antibiotic Sazi Iran Company
Mahmoodreza Akbarpour - Antibiotic Sazi Iran Company
خلاصه مقاله:
Babak Pourrostam - Antibiotic Sazi Iran Company
Faramarz Asghari - Antibiotic Sazi Iran Company
Marzieh sadatshahabi - Antibiotic Sazi Iran Company
Mahmoodreza Akbarpour - Antibiotic Sazi Iran Company
Pharmaceuticals & fine chemicals are one of the most polluting industries, due their large consumption of energy and chemicals, and also high volumes production of organic waste and byproducts. Enzymatic processes, however, offers potential opportunities for changing the industry towards more environmentally friendly and efficient operations compared to the conventional chemical methods. The present work is replacement of traditional organic process by a green biocatalytic alternative in industrial production of Cephalexin. Cephalexin is synthesized with 7-amino-3-deacetoxycephalosporanic acid (7-ADCA) and D(–)-phenylglycine methyl ester (PGME) using immobilized penicillin G acylase in aqueous medium
کلمات کلیدی: Green manufacturing, Aqueous medium, Penicillin-G acylase, β-Lactam antibiotic, Cephalexin
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/711043/