Effects of vitamin C and E as antioxidants on breast cancer patients under chemotherapy

Introduction:Reactivation of oxygen and nitrogen molecules by anti-neoplasticagents can be toxic side effects of chemotherapy.It is a way of treatment for them andincrease quality of life. Supplemental antioxidant administration of medications ordiet plus chemotherapy cytotoxin could be modified or even reduce its effects.Reducethe physiological barrier of antioxidants during chemotherapy resulted in increasedoxidative stress and damage by free radicals are organic.Methods:This review article citing articles from several online (pubmed, ovid, ..) andrapeutics & clinical pharmacy the literature is provided. TheConclusion:In untreated patient(not accept vit c&E) looked low level ofantioxidant(p<0.001)andlow level of gloutamin(p<0.001)and increase of fatpreoxidation(p<0.001)and DNA damage