Diagnosis of Circular Cancer Stem Cell by Microfluidic System

Cancer is a disease that is spreading day by day around the world and taking lives of thousands of people every day. Detection of late cancer leads to the death of many cancer patients, so it is very important to detect it at an earlier stage. Investigating cell-cell interaction, cell-Nano composite, stem cell and cancer cell migration, studying the interaction of cell-scaffold, drug-cell and the effect of mechanical factors on microfluidic systems of perfusion can be checked. The Labyrinth system, is one of the newest techniques that are available to isolate cancer cells from thousands of blood cells, and this can be used to isolate cancer stem cells from blood cells in this system we could labeled desired cells and isolate circulating tumor cells (CTCs) by using the combination of long loops and sharp corners to focus both CTCs and white blood cells (WBCs) . Using these systems, like these, cancers can be detected at much lower levels. one or two cells circulating in the bloodstream. Multiple single-cell techniques have emerged in recent years, making the genome, transcriptome, and proteome of single cells. Designing this kind of device is inspired by the Labyrinth in Greek mythology, an elaborate structure with numerous turns and corners built to hold the Minotaur. This method can be the key to the development of new cancer treatments. If you can isolate invasive cancer cells (from other cells), you have a better chance of developing a cancer treatment.

Keywords:

Microfluidic , Cancer , Stem Cell