Rezvan Esmaeili - PhD, Molecular genetics Head of Genetics department, Breast cancer research center, Motamed cancer institute, ACECR, Tehran, Iran

Treatment of cancer involves patients with side effects that detriments their quality of life. Moreover, the efficiency of them may not enough to prevent recurrence and metastasis. Personalized medicine in breast cancer like other diseases uses information about a person’s genes, proteins and environment to prevent, diagnose and treat disease. Recent genes and molecules are about to predict not only treatment response, but also the severity of common cancer related symptoms. In this talk the personalized options for optimal treatment choice and dosage and managing the related symptoms in order to enhance the quality of life of breast cancer patients will discussed. The following areas are discussed properly. Treatment related issues such as Gene Expression Profiling Techniques in the Optimization of Drug Choice, Use of Pharmacogenomics in Predicting Response to Chemotherapeutic Drugs, Circulating Tumor Cells, MicroRNA in Triggering Drug Release, Biomedical Engineering Tools in Intervention Design, Optimizing Radiation Dose in Radiotherapy, and quality of life issues such as Premature Menopause or Chemotherapy-Induced Menopause, Chemotherapy-Induced Peripheral Neuropathy, Cognitive Dysfunction