Association of Breast Cancer and its Therapy with Candida Infection

Publish Year: 1393
نوع سند: مقاله کنفرانسی
زبان: English
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ICBCMED10_070

تاریخ نمایه سازی: 21 اردیبهشت 1397

Abstract:

Some studies have shown evidence of Candida infection co-existing with malignancy and immunosuppressant disease due to debilitating diseases and nosocomial causes. Oncologists give patients drugs or undergoing radio or chemotherapy which make their yeast infections worse. In thisretrospective study, the authors did an extensive literature review of published studies about association of breast cancer and candida infection during recent 50 years. Studies showed Candida thrives in a low oxygen environment and produce toxin and stimulate breast cancer. Some researchers demonstrated the relationship between renal candidiasis and breast cancer. Severe suppression of the immune system andinflammation in the body in breast cancer patients lead to an increased risk of Candidal infection in their cavities. Candida can cause blood sugar imbalances which are associated with cancers due to immune system suppression. On the other hand, deep tissue fungal growth in breast may be commonly diagnosed as cancer. Candida can ferment sugar and cancer cells rapidly proliferate in the presence of fermented sugar. Candida can be phagocytized by breast cancer cells. Estrogen and corticosteroid drugs reduce function of Thymic gland and promote Candidal growth. However, some studies show Tamoxifen and Sodium bicarbonate given to prevent breast cancer from returning have anti-candida properties. Some studies supported the idea that candida species associate with breast cancer; however, they have presented problems with experimental settings. More effort to assess the role of candida in carcinogenesis is needed. We propose preventing and treating candida infections may possibly stop oreven eliminate certain types of cancers.

Authors

Seyyed Saeed Aghili

Student of Medicine, Faculty of Medicine, Shahid Beheshti University of Medical Science, Tehran,Iran.

Seyed Reza Aghili

Ph D Student and Faculty Member of Medicine, Department of medical Mycology & Parasitology,Faculty of Medicine, Mazandaran University of Medical Science, Sari, Iran.

Bahar Salmanian

Member of Farhangian University, Department of Sciences, Sari, Iran.