The role of Axillary Dissection for Breast Cancer in Old women; A Meta-analysis ofRandomized Clinical Trials
Publish place: 10th International Breast Cancer Congress
Publish Year: 1393
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
ICBCMED10_100
تاریخ نمایه سازی: 21 اردیبهشت 1397
Abstract:
We performed this meta-analysis to assess the effectiveness and safety of axillary dissection in old women. Methods: The Cochrane Library, PubMed, EMBASE and Chinese Biomedical Literature Database were searched and all randomized controlled trials of axillary dissection in old women (at least 60 years old) were considered. Meta-analyses were completed using RevMan5.1. Results: Three eligible randomized controlled trials (RCTs) including 5,337 patients were considered. There was weak evidence in favour of axillary dissection (AD) in old women. The metaanalysis showed that the overall survival (OS) after 1, 3, 5 and 7 years and the disease free survival (DFS) after 1, 3 and 5 year were not statistically significantly different between AD and no AD groups. However, there was a difference in the 7 year DFS. Conclusions: Axillary dissection did not provide survival benefit to the old women with breast cancer analysed. Therefore, axillary dissection is not wellindicatedin old women with breast cancer.
Keywords:
Breast cancer - old women - axillary dissection - meta-analysis - randomized controlledtrials
Authors
A.SH Davoudi
Department of Radiation Oncology ,ShohadaTajrish Hospital ,Shahid BeheshtiUniversity of Medical Sciences , Tehran, Iran
B Mofid
Department of Radiation Oncology ,ShohadaTajrish Hospital ,Shahid BeheshtiUniversity of Medical Sciences , Tehran, Iran
A Rakhsha
Department of Radiation Oncology ,ShohadaTajrish Hospital ,Shahid BeheshtiUniversity of Medical Sciences , Tehran, Iran
M Hoshyari
Department of Radiation Oncology ,ShohadaTajrish Hospital ,Shahid BeheshtiUniversity of Medical Sciences , Tehran, Iran