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Investigation the effect of Cytarabin, and Iranian and European olive polyphenol extract on gene expression in MCF7 apoptosis pathway

تعداد صفحات: 1 | تعداد نمایش خلاصه: 68 | نظرات: 0
سال انتشار: 1394
کد COI Paper: ICBCMED11_105
زبان Paper: Englishglish
نسخه کامل Paper در کنفرانس ارائه نشده است و در دسترس نیست.

مشخصات نویسندگان Paper Investigation the effect of Cytarabin, and Iranian and European olive polyphenol extract on gene expression in MCF7 apoptosis pathway

Alireza Amiri-Nowdije - Ph.D student, National Institute of Genetic Engineering & Biotechnology,Tehran, Iran.
Mehdi Hosseini-Mazinani - Member of scientific board, National Institute 0f Genetic Engineering & Biotechnology,Tehran, Iran.
Masood Soleimani - Member of scientific board, Tarbiat modarres University,Tehran, Iran.

چکیده Paper:

Introduction : Olive due to containing oleic acid and polyphenolic compounds, as a functional food against many chronic diseases, such as cardiovascular complications, cancer and neurodegenerative diseases can have preventive, restoration or treatment effects that doesn t have many problems and side effects of chemical drugs. Materials and Methods: In this study, the effect of Iranian and European Olive polyphenolic extracts compared to anticancer drug cytarabine on the MCF7 was evaluated. Assessment of the cell death and gene expression in apoptotic pathway has been done by MTT assay and Real-time PCR. Results: The results show the good capabilities of Olive polyphenolic extract on apoptosis induction. Bax and bcl2 genes expression showed a significant change. Discussion and conclusion: Our results showed that the polyphenolic extract oil compared to the drug has a significant effect on the growth of cancer cells and apoptosis induction. Side effects of chemotherapy drugs is one of the serious challenges in the treatment and control of tumor development in cancers particularly breast cancer, so olive and its extracts can be used as a adjuvant in the treatment and reducing side effects of chemotherapy drugs.

کلیدواژه ها:

cell line, olive polyphenolic extract, apoptosis, Real-time PCR, cytarabine

کد Paper/لینک ثابت به این Paper

برای لینک دهی به این Paper می توانید از لینک زیر استفاده نمایید. این لینک همیشه ثابت است و به عنوان سند ثبت Paper در مرجع سیویلیکا مورد استفاده قرار میگیرد:

https://civilica.com/doc/726765/

کد COI Paper: ICBCMED11_105

نحوه استناد به Paper:

در صورتی که می خواهید در اثر پژوهشی خود به این Paper ارجاع دهید، به سادگی می توانید از عبارت زیر در بخش منابع و مراجع استفاده نمایید:
undefined, undefined و undefined, undefined و undefined, undefined,1394,Investigation the effect of Cytarabin, and Iranian and European olive polyphenol extract on gene expression in MCF7 apoptosis pathway,یازدهمین کنگره بین المللی سرطان پستان,Tehran,,,https://civilica.com/doc/726765

در داخل متن نیز هر جا که به عبارت و یا دستاوردی از این Paper اشاره شود پس از ذکر مطلب، در داخل پارانتز، مشخصات زیر نوشته می شود.
برای بار اول: (1394, Amiri-Nowdije, Alireza؛ Mehdi Hosseini-Mazinani و Masood Soleimani)
برای بار دوم به بعد: (1394, Amiri-Nowdije؛ Hosseini-Mazinani و Soleimani)
برای آشنایی کامل با نحوه مرجع نویسی لطفا بخش راهنمای سیویلیکا (مرجع دهی) را ملاحظه نمایید.

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