The survey of relationship between fertility factors and breast cancer in women with Breast Cancer reffered to dependent clinics the UMS in tehran city

Introduction: Breast cancer is the most cancer and first the cause of mortality from cancer at women,that its prevalence is increasing.The identifying of risk factors of breast cancer has important role in recognition of high risk persons and prevention of disease,therefore this study conducted for determining of relationship between factors dependent to obstetric and gynecologic history with breast cancer. Material & Methods: The current research is a comparrative discriptive study, that sample of case group (100 women) selected from between affected women become mastectomy (radicalor lower of radical) and reffered to centers of chemotherapy and radiotherapy of cancer institute and shohada hospital. Also the samples of control group (100 women) selected from between references to breast exam clinics of the same centers, that had been rejected breast cancer in them though assessment of mamography, sonography or breast exam by specialized physician. For data collection was used of questionair including of demographic data and fertility factors(age of menarch,unregularity of mensturation,age of marriage,number of pregnancy,number of abortion,brest feeding history,using of OCP,kind of OCP,years of OCP using,HRT history,age of starting and finishing HRT,age of first and final pregnancy). Results: Data analisis showed there was significant relationship between breast cancer with age of menarch ≤12 years(OR=5.2), unregularity of mensturation(OR=2.3), number of abortion(OR=3.6), age of marriage<20 years(OR=2.6),lack of brest feeding(OR=2.8),and using of OCP > 5 years(OR=3.4) (p<0.05). Discussion and Conclusion: In various studies has emphasized on role of investigated factors and to seem consider the majority of this factorsare controlable can with planning teaching programms and medical follow up effective stepfor decreasing rate of breast cancer to take.

Keywords:

Fertility Factors , Breast Cancer