Effect of hydroalcoholic extract of Nepeta assurgens on serum levels of VLDL in normal rats

So far, in Iran 81 species of Lamiaceae family have been registered; among them 12 species belong to Nepeta genera. Among different species of this genus, Nepeta assurgenes is considered as a medical plant with anticonvulsant, mucus, diuretic, anti- asthma, cough, fever properties is very important. With regard to antioxidant assurgens, in this study, Effect of hydroalcoholic extract of N. assurgens on serum levels.properties of plant N very low density lipoprotein (VLDL) in normal rats were investigated.In this study, Normal rats were divided into 2 groups received 100 mg/kg extract and distilled water (0.5 mL) by gavage for 14 days, respectively. After treatments, rats were sacrificed and serum levels of lipids were evaluated After, serum levels of VLDL was also calculated using Freidewald formula. Results.by spectrophotometry showed that administration 100 mg/kg extract of N. assurgens in normal rats for 14 days had no significant on serum levels of VLDL (p > 0.05) effect. Thus, hydroalcoholic extract of N. assurgens had no effect administration extract on serum levels of VLDL in normal rats.

Keywords:

Nepeta assurgens , lipoprotein , VLDL , normal rats