Pathogenesis of edema in nephrotic-nephritic syndrome, new edema

Nephritic syndrome is a collection of signs (syndrome) associated with disorders affecting the kidneys more specifically glomerular structure, characterized by: having small pores in the podocytes, large enough to permit proteinuria and hematuria (RBC, RBC cast), leukocyturia (WBC cast).Edema is shown in the nephritic syndrome by accumulation of salt and water in the vessles with overload manifestations. Salt restriction during the acute phase to control edema and volume related HTN with diuretic and antihypertensive drugs are recommended.Nephrotic syndrome is a syndrome with hypoalbuminemia, hyperlipidemia, edema and massive proteinuria. Edema occurrence in nephrotic syndrome is different from nephritic syndrome. Edema is seen in these patients by accumulation of salt and water in extravascular space. Salt restriction is advised for the prevention and treatment of edema, a very low salt diet is only necessary in cases of massive edema (33mg/kg/day). Fluid restriction is recommended in moderate to severe hyponatremia (PNa<125 meq/l), continue weight gain against salt restriction