Vitamin D Deficiecy as an indicator of artificial light poisoning , A historic narrative view of vitamin d and human displacement

Life begins to evolve in the oceans over 1 billion years ago. Phytoplankton as an earlier habitant of earthtook advantage of sunlight and used it as an energy source to generate carbohydrate and makes vitamin D .Role of vitaminD in this tiny factory of photosynthesis is protection of important components of cell, DNA and RNA and amino acids with double bonds.The capacity of vitamin D to absorb ultraviolet B in phototoxicwavelength of 290nmmakes it a vital natural sunscreen for cells(1).Meanwhilethis hormone is a photo chemical to signal organisms to move from surface to deep ocean in order to prevent excess exposure to photo toxic dosage of ultra violet B.(signal for movement& protection)(2).All vertebrate need vitamin Dfor movementthey make it from skin exposure to sun or consume precursors from sea staff that eat phytoplankton in food chain or from plants.(3)Human and vitamin D Vitamin d has had huge impact on evolution of human skin color .By gradual movementtoward in higher latitude from equatorialarea only femaleswho have evolvedto lighter skin were able to produce enough vitamin d, and have a normal pelvis anatomy to normallydeliver a healthy baby;female with low vitamin d (probably dark skin with low vitamin ) were excluded from reproductive cycledue to maternal complications(4).This is the reason that residents of northern latitudes have lighter skin color now.Skin pigmentation determined by one favoringphoto protection near the equator and other favoring vitamin D production nearer the pole.Two other histories from movement and vitamin D back to the industrial revolution .In 1600 majority of big cities in Europe hosted people who immigrated from rural to urban area ,this movement accompanied by living in home close proximity to each other .Coal consumptionmade city heavily polluted ,reports showed more than 80 %of children in these cities had rickets(5). In1822 one century before Hess discovery of sunlight exposure as a treatment of rickets (1923),Sniadecki in Warsaw said lack of sun light is the reason of disease what was lateraccepted (6).Force movement of black people is anotherhistory ofmovement and vitamin d .The slave trade took blacks out of Africa and settled them, among other places, across North America, Canada and Northern Europe where for months of the year sun rays strike less directly, drastically reducing the amount of sunlight which their skin were not adapted and was necessary to make adequate vitamins d . in that time medical report described a disease that is similar to hypocalcemia of vitamin d deficiency,it was called black (7)diseases that seen in black slave after a period of settling; with neurological symptoms and psychosis .The reason was fast displacement of black from one continent to other continent , it was slavery disease I called it. Through time, human adaptations to different solar beam have become more cultural than natural. Rapid human migrations with industrial revolution, increasing urbanization in modern life, and changes in lifestyle have created mismatches between skin pigmentation and environmental conditions(8) .In the beginning of life adequate vitamin D was a signal for movement, force or rapid displacement in human history was accompanied with vitamin D deficiency .Is it possible that vitamin d deficiency again be a sign of premature shift from one place to other place Or new type of slavery not limited to black but include all races black, white and yellow and not limited to one continent but pandemic. Vitamin d deficiency may be an alarmingsignal for abnormalmankind displacement from outdoor activities and sun exposureopportunity.it will be more important when we realize during sun exposure several other by product produce in skin likeluminestrol and tachestrol which have anti proliferative effect and regulate epidermal growth ,in the other words vitamin d production is only 15% of by products that produce during solar exposure and other photo product has other benefit which will turn out in the future(9). If we have enough sun exposure in the environment and do not receive any vitamin D supplement, then adequate vitamin D (levels> 30ng/dl) level will be a marker of adequacy of outdoor activity . Prescription of vitamin d to normalize 25 hydroxy vitamin D is a very simplistic approach to the problems that took place in our history for several times .Let me leave you with a question what is the hazard of indoor activity Evidences show indoor activity and lack of sun exposure is a risk for premature death like obesity, smoking and inactivity .It remains to reveal the impact of this behavior by huge human cost in future.What do we use instead of natural sun light when we engage in indoor activity Is itour new environmental hazard