Investigation of The Association of Chlamydia Infection in Infertile Women With Biomarkers

Background: The present study aimed to identify Chlamydia trachomatis bacteria in infertile women and its correlation with AMH and MFGE8 markers in women referring to Alhadi Hospital in Shoushtar in 2017. Method: A descriptive study of analytical type. 50 infertile people aged 15-45 years old and 25 healthy fertile individuals referred to the women s clinic were selected as the sample size with inclusion criteria and divided into 4 groups. The serum levels of chlamydia (IgG) and hormones with The use of ELISA was analyzed. Data were analyzed using statistical tests and spss21 software. Results: Out of 75 participants, 43 infertile people with Chlamydia and 26 infertile without chlamydia and 16 infertile people with Chlamydia, 15 were fertile without Chlamydia. There was a significant correlation between chlamydia and infertility by independent t-test. P <0.05. Also, for the study of biomarkers, only MFG-E8 was significantly associated with Chlamydia (P = 0.001). However, there was no significant difference between the two fertility and infertile groups in terms of MFG-E8. Discussion and Conclusion: The MFG-E8-AMH is an ideal marker for ovarian function than other hormonal markers. There was no significant difference in the level of AMH in relation to Chlamydia infection

Keywords:

Infertility , Chlamydia trachomatis , AMH , MFG-E8