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Title

Vitamin D Deficiency: A Neglected Truth in Iran

Year: 1396
COI: JR_JNFS-2-2_001
Language: EnglishView: 216
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Authors

Nahid Ramezani-Jolfaie - MSc, Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran- Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Amin Salehi-Abargouei - PhD, Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran- Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Abstract:

Vitamin D (vit D) is a fat-soluble steroidwhich includes two forms: vitD2 (ergocalciferol) and vit D3 (cholecalciferol).The former is provided from plant and the latter istaken from animal sources (Shao et al., 2012). VitD is obtained from natural synthesis in the skinand also from some dietary sources such as oilyfish, eggs, fortified products (dairy, cereals, soy),and oral supplements (Jolfaie et al., 2016, Kennelet al., 2010). Finally, it is activated biologicallyduring hydroxylation process in the liver andkidneys (Shao et al., 2012).Vit D has essential physiological functionsfor maintaining mineral homeostasis (Chung et al.,2011). Indeed, vit D deficiency can contribute toseveral musculoskeletal disorders, such as ricketsin children, osteomalacia, osteopenia, osteoporosis,and fractures in adults (Moher et al., 2001). Inaddition, the association between vit D deficiencyand many diseases including cancers, infections,autoimmune diseases, diabetes mellitus, andcardiovascular diseases have been studied (Hilgeret al., 2014, Norman, 2008). The normal level of25(OH)D (the dominant vit D metabolite incirculation representing vit D status) is considered20 ng/ml (50 nmol/L) and less than this value isclassified into the deficiency category(Christodoulou et al., 2013, DeLuca, 2004). Themost important factors in deficiency of vit D aredecreased sun exposure, insufficient vit D intake,and increase of age (Gaugris et al., 2005).Moreover, high risk of vit D deficiency has beenobserved in special groups and conditions such aschildren, pregnant and postmenopausal women, aswell as elderly people (Shao et al., 2012); diseasesassociated with fat mal-absorption (e.g., Crohn’sdisease) (Kennel et al., 2010); and disturbingconditions of parathyroid, liver, or kidneyfunctions (Kathleen Mahan et al., 2012).V

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This Paper COI Code is JR_JNFS-2-2_001. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

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Ramezani-Jolfaie, Nahid and Salehi-Abargouei, Amin,1396,Vitamin D Deficiency: A Neglected Truth in Iran,https://civilica.com/doc/764246

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Type of center: علوم پزشکی
Paper count: 3,482
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