Preparation and Stabilization Methods of Liposomes as drug carriers
عنوان مقاله: Preparation and Stabilization Methods of Liposomes as drug carriers
شناسه ملی مقاله: ICHEC06_417
منتشر شده در ششمین کنگره بین المللی مهندسی شیمی در سال 1388
شناسه ملی مقاله: ICHEC06_417
منتشر شده در ششمین کنگره بین المللی مهندسی شیمی در سال 1388
مشخصات نویسندگان مقاله:
Fatemeh Anisi - Department of Biotechnology Engineering, Faculty of Chemical Engineering, University of Tehran
Ghassem Amoabediny - Department of Biotechnology Engineering, Faculty of Chemical Engineering, University of Tehran
Mohsen Rahimi - Department of Biotechnology Engineering, Faculty of Chemical Engineering, University of Tehran
خلاصه مقاله:
Fatemeh Anisi - Department of Biotechnology Engineering, Faculty of Chemical Engineering, University of Tehran
Ghassem Amoabediny - Department of Biotechnology Engineering, Faculty of Chemical Engineering, University of Tehran
Mohsen Rahimi - Department of Biotechnology Engineering, Faculty of Chemical Engineering, University of Tehran
Liposome is used as a carrier in many different aspects like pharmacy and as a drug carrier but the main objective is to achieve selective, and sufficiently high, localization of active drug at disease sites such as tumors and inflamed tissues. Many types of liposomes of different lipid composition and different sizes were prepared. These liposomes varied in their liposome-forming lipid, being with and without cholesterol and /or lipopolymer, their size and method of preparation. The approaches for preparing these different liposomes formulation varies in their lipid hydration and downsizing. At this paper we present different liposomes with different preparation methods and the analysis on what researchers done. Next the parameters and their effect on liposome is well-analyzed. The methods to overcome instability causes are indicated too.
کلمات کلیدی: Liposome, Sonication, Stability, Extrusion, Homogenization
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/77690/