EVALUATION OF ANTIBIOTIC RESISTANCE IN ESCHERICHIA COLI STRAINS ISOLATED FROM URINARY TRACT INFECTIONS IN IMAM REZA HOSPITAL, BOJNURD, IN 1396

Background and Aim:E. coli is a member of the Enterobacteriaceae family, which is part of the normal flora of the gastrointestinal tract of humans. This bacterium is a most common cause of urinary tract infections. Given the importance of urinary tract infection and may spread to the bloodstream and other parts of the body correct and efficient treatment is very important. The aim of this study was to determine antibiotic resistance in Escherichia coli strains isolated from urinary tract infections Imam Reza Hospital, Bojnurd, in 1396.Methods:After isolation and confirmation of strains of E. coli in Urine samples with conventional approaches, investigation of antibiotic resistance performed by disk diffusion method in accordance with CLSI standards using amikacin, ciprofloxacin, imipenem, ampicillin, ofloxacin, trimethoprim-sulfamethoxazole, gentamicin, nitrofurantoin, ceftriaxone, cefotaxime, Nalidixic acid, cefazolin and amoxicillin disks.Results:In the 1396 a total of 1754 urine culture 193 (11%) were positive. Among these 154 cases (79/8%) were E. coli. Of these isolates 52.8% were resistant to amikacin, 22.3% to ciprofloxacin, 0% to imipenem, 48.2% to ampicillin, 88.1% to ofloxacin, 51.8% to co-trimoxazole, 23.8% to gentamicin, 29% to nitrofurantoin, 3.6% to Nalidixic acid, 77.7% to cefazolin and 88.1% were resistant to amoxicillin.Conclusion:According to results, relatively high rates of antibiotic resistance are seen compared to previous reports. Given the importance of E. coli in urinary tract infections, need to revise and correct diagnosis and appropriate treatment in order to reduce the spread of antibiotic resistance of urinary tract infections can be felt.

Keywords:

Escherichia coli , antimicrobial resistance , urinary tract infection