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EVALUATING THE SIMULTANEOUS IMPACT OF NANOPARTICLES WITH NETTLE EXTRACT AGAINST KLEBSIELLA THROUGH A CHECKERBOARD METHOD

تعداد صفحات: 1 | تعداد نمایش خلاصه: 157 | نظرات: 0
سال انتشار: 1397
کد COI Paper: MEDISM19_146
زبان Paper: Englishglish
نسخه کامل Paper در کنفرانس ارائه نشده است و در دسترس نیست.

مشخصات نویسندگان Paper EVALUATING THE SIMULTANEOUS IMPACT OF NANOPARTICLES WITH NETTLE EXTRACT AGAINST KLEBSIELLA THROUGH A CHECKERBOARD METHOD

Mahsa Dadgar - Department of Biology, East Tehran Branch, Islamic Azad University, Tehran, Iran
Sara Minaeian - Antimicrobial Resistance Research Center, Institute of Immunology and Infectious Diseases, Rasoul-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
Somayeh Samimi - Ebnemasouyeh pharmaceutical company
Meisam Sadeghpour Karimi - Center of Excellence in Electrochemistry, University of Tehran, Tehran, Iran

چکیده Paper:

Background and Aim:Klebsiella pneumonia is seen numerously in people hospitalized at the hospitals as well as people with weak immunity, so antibiotic resistance is a serious threat in this bacteria. Silver nanoparticles and many herbal extracts influence a wide range of bacteria due to the large antibacterial effect. The purpose of this study is to investigate the simultaneous effect of silver nanoparticles with nettle extract against Klebsiella bacteria through a checkerboard method.Methods:350 samples were collected from patients hospitalized in all wards of Rasool-e-Akram hospital. 112 Klebsiella strains were isolated using biochemical tests. Among them, resistant isolates were separated. The effects of silver nanoparticles, nettle extract, the combination of nettle extract and silver nanoparticles on the isolated bacteria were investigated using MIC and checkerboard methods.Results:The results showed that MIC for nettle extract is 0/7mg/ml against both isolates and is 0/78mg/ml for silver nanoparticles against ATCC isolate and is 3/125 mg/ml against MDR isolate. Simultaneous application of silver nanoparticles and nettle extract has a synergistic effect against the resistant isolate and an incremental effect against the standard isolate.Conclusion:Due to the increasing number of hospital infections and because bacteria are resistant against existing antibiotics, it is important to find a substitute for antibiotics with new materials having antibiotic characteristic, in near future. Because their production is cost effective and they have a good effect on resistant bacteria, they can be used in antibiotic treatments and their antibacterial effect can be exploited.

کلیدواژه ها:

silver nanoparticles, Klebsiella, nettle extract, synergism

کد Paper/لینک ثابت به این Paper

برای لینک دهی به این Paper می توانید از لینک زیر استفاده نمایید. این لینک همیشه ثابت است و به عنوان سند ثبت Paper در مرجع سیویلیکا مورد استفاده قرار میگیرد:

https://civilica.com/doc/782485/

کد COI Paper: MEDISM19_146

نحوه استناد به Paper:

در صورتی که می خواهید در اثر پژوهشی خود به این Paper ارجاع دهید، به سادگی می توانید از عبارت زیر در بخش منابع و مراجع استفاده نمایید:
undefined, undefined و undefined, undefined و undefined, undefined و undefined, undefined,1397,EVALUATING THE SIMULTANEOUS IMPACT OF NANOPARTICLES WITH NETTLE EXTRACT AGAINST KLEBSIELLA THROUGH A CHECKERBOARD METHOD,نوزدهمین کنگره بین المللی میکروب شناسی ایران,Tehran,,,https://civilica.com/doc/782485

در داخل متن نیز هر جا که به عبارت و یا دستاوردی از این Paper اشاره شود پس از ذکر مطلب، در داخل پارانتز، مشخصات زیر نوشته می شود.
برای بار اول: (1397, Dadgar, Mahsa؛ Sara Minaeian و Somayeh Samimi و Meisam Sadeghpour Karimi)
برای بار دوم به بعد: (1397, Dadgar؛ Minaeian و Samimi و Sadeghpour Karimi)
برای آشنایی کامل با نحوه مرجع نویسی لطفا بخش راهنمای سیویلیکا (مرجع دهی) را ملاحظه نمایید.

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نوع مرکز: azad university
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