METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) AND STAPHYLOCOCCAL CASSETTE CHROMOSOME MEC GENOTYPES (SCCMEC) IN FASA, FARS

Publish Year: 1397
نوع سند: مقاله کنفرانسی
زبان: English
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MEDISM19_199

تاریخ نمایه سازی: 13 مهر 1397

Abstract:

Background and Aim:Staphylococcus aureus is one of the most important pathogenic bacteria causing community and hospital acquired infections. Treatment of this pathogen is complicated because of resistance to many antimicrobial drugs. Methicillin-resistant S. aureus (MRSA) is considered as a cause of clinically infectious disease in public health. The aim of this study is determination of the antibiotic resistance pattern in MSRA strains (based on SCCmec genotyping) isolated from patient in hospitals of Fasa.Methods:Staphylococcus aureus is one of the most important pathogenic bacteria causing community and hospital acquired infections. Treatment of this pathogen is complicated because of resistance to many antimicrobial drugs. Methicillin-resistant S. aureus (MRSA) is considered as a cause of clinically infectious disease in public health. The aim of this study is determination of the antibiotic resistance pattern in MSRA strains (based on SCCmec genotyping) isolated from patient in hospitals of Fasa.Results:Among 164 isolated S. aureus, 78 samples were MRSA. Sensivity pattern of Antibiotic were reported as: chloramphenicol (19.2%), gentamicin (74.4%), kanamycin (85.9%), erythromycin (89.7%), tetracycline (92.3%), ciprofloxacin (92.3%), tri-methoprime (92.3%), methicillin (100%) and cefoxitin (100%); there were any resistance to vancomycin. Most and less common genotypes of SCCmec were related to II and IV types, respectively.Conclusion:Easy access and improper administration of antibiotics and also incomplete course of treatment in infectious disease can led to development of multi-resistance isolates such as MRSA.

Authors

Abbas Abdollahi

Department of Microbiology, Fasa University of Medical Sciences

Sohrab Najafipoor

Department of Microbiology, Fasa University of Medical Sciences