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CONSTRUCTION OF AN ALGINATE BASE HYDROGEL AND EVALUATING HEALING ACTIVITIES OF MENTIONED COMPONENT AS LOCAL OINTMENT WERE THE MAIN OBJECTIVES OF THE CURRENT STUDY

تعداد صفحات: 1 | تعداد نمایش خلاصه: 163 | نظرات: 0
سال انتشار: 1397
کد COI Paper: MEDISM19_344
زبان Paper: Englishglish
نسخه کامل Paper در کنفرانس ارائه نشده است و در دسترس نیست.

مشخصات نویسندگان Paper CONSTRUCTION OF AN ALGINATE BASE HYDROGEL AND EVALUATING HEALING ACTIVITIES OF MENTIONED COMPONENT AS LOCAL OINTMENT WERE THE MAIN OBJECTIVES OF THE CURRENT STUDY

Bahman Mirzaei - Department of Medical Microbiology and Virology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Somayeh Etemadian - Department of Medical Engineering, Faculty of Engineering Maziar University, Noor, Iran
Hamid Reza Goli - Department of Medical Microbiology and Virology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Sara Bahonar - Department of Medical Microbiology and Virology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran

چکیده Paper:

Background and Aim:Developing a strategy for making the alginate base hydrogel components against burned wound infections could be promising for healing the mentioned wounds followed by elimination of the biofilm forming bacteria colonization.Construction of an alginate based hydrogel and evaluating healing activities of the mentioned component as local ointment were the main objectives of the current study.Methods:Following the collection of the honey from three different provinces of Iran, the components and structures of the collected materials were analyzed taking advantage of INSO-92 procedure subsequently, antibacterial effect of diluted three different kinds of honey against wild-type bacterial species got evaluated via agar well diffusion method. An alginate base hydrogel was prepared by the use of calcium chloride as a linker between the alginate and honey functional groups. Then, component was structurally analyzed by Fourier Transform Infrared spectroscopy (FTIR). Afterward, under in vivo conditions, the healing activities of prepared ointment were studied in infected burned rat models.Results:According to the antibacterial effect of the honeys, 75% diluted thymol based honeys collected from Damavand province were the most efficient ones. Furthermore, it was the healing activity of mentioned ointment was proven in vivo studies. The difference between 1600-1800 wave numbers in constructed alginate-based hydrogel alginate and honey because of C=O bond variations structurally confirmed proper construction of hydrogel. The hydrogel was the better healing activity in rats burned wound too.Conclusion:In conclusion the promising efficiency of alginate-based hydrogel in an elimination of bacterial infections was confirmed as the main aim of the current survey.

کلیدواژه ها:

burned wound infections ,honey, alginate based hydrogel

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https://civilica.com/doc/782683/

کد COI Paper: MEDISM19_344

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undefined, undefined و undefined, undefined و undefined, undefined و undefined, undefined,1397,CONSTRUCTION OF AN ALGINATE BASE HYDROGEL AND EVALUATING HEALING ACTIVITIES OF MENTIONED COMPONENT AS LOCAL OINTMENT WERE THE MAIN OBJECTIVES OF THE CURRENT STUDY,نوزدهمین کنگره بین المللی میکروب شناسی ایران,Tehran,,,https://civilica.com/doc/782683

در داخل متن نیز هر جا که به عبارت و یا دستاوردی از این Paper اشاره شود پس از ذکر مطلب، در داخل پارانتز، مشخصات زیر نوشته می شود.
برای بار اول: (1397, Mirzaei, Bahman؛ Somayeh Etemadian و Hamid Reza Goli و Sara Bahonar)
برای بار دوم به بعد: (1397, Mirzaei؛ Etemadian و Goli و Bahonar)
برای آشنایی کامل با نحوه مرجع نویسی لطفا بخش راهنمای سیویلیکا (مرجع دهی) را ملاحظه نمایید.

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