R .A sahib - Department of Biology, Faculty of Science /University of Kufa, Najaf- IRAQ

This study is conducted to reveal the effects of oral administration of C.herbarium of two compounds has been toxic effects on the reproductive hormonal, and the ability of ascorbic acid to decrease growth of C.herbarum. Fungi species which were isolated from indoor buildings were Cladosporium herbarum, Aspergillus niger, Alterneria sp. and Fusarium sp. C. Herbarium was founded more visible and frequent in indoor buildings and reached to about (70,60)% respectively .It is observed that C.herbarium is able to produce two compounds has been significant toxic effects on biochemical blood parameters which are causing decreased in the level of luteinizing hormone (LH) and follicle stimulating hormone (FSH) which is causing significant effects, as compared with the control group. C.herbarium produced two compounds which have been toxic effects on the reproductive hormones, causing decreased in the (LH), (FSH) and ability of ascorbic acid to decrease growth of C.herbarum.

Cladosporium herbarum, LH, FSH, Ascorbic acid