Gastric Cancer Epidemiology from 2012 to 2017 in Mashhad, Iran

Background and Aim: Gastric cancer (GC) is characterized as the fourth most common cancer and second leading cause of cancer mortality in the world. Epidemiological studies have been done all around the world but the exact GC epidemiology still remains unclear in Mashhad. The purpose of the present research was to assess the GC epidemiology in Mashhad, Iran. Materials and Methods: In this study, 11543 individuals were employed from July 2012 to December 2017. The primary tumor was classified as the basis of either findings of endoscopic and pathologic results. The patients were first screened then endoscopy done for evaluation of symptoms related to upper gastrointestinal tract. Demographic data extracted from charts. After data entering, a controller rechecked information. Data was analyzed with SPSS version 16.0 (P < 0.05).Results: The prevalence of endoscopic carcinoma among 11543 subjects was 5.6%. Totally, 47.3% patients were male and 52.7% were female. The incidence of carcinoma was 2% and 8% in women and men, respectively. By Chi-Square test, there is significant difference in male and female (P = 0.0001). Independent t-test showed significant correlation between age and carcinoma (P = 0.0001). The age range of patients with carcinoma varies from 6 to 92 years with the mean of 64.21 ± 14.45 years. By Chi-Square test, there is a significant correlation between prevalence of carcinoma and regions of gastric carcinoma (P = 0.0001). The most frequent region of carcinoma was mucosal area. The prevalence of carcinoma was statistically higher in H.pylori non-infected individuals (P = 0.0001). Conclusion: According to main findings in the research, GC epidemiology in Mashhad, mucous area was reported as the most involved area.

Keywords:

Gastric Cancer , Helicobacter pylori , Prevalence