Hamidreza Hasani - Eye Research Center, Rassoul Akram Hospital, Iran university of Medical sciences, Tehran, Iran

Purpose: To evaluate the clinical effectiveness of BlephEx in treatment of obstructive meibomian gland dysfunction (MGD). Methods: In this retrospective study, 312 lids of 78 patients (49 female and 29 male) with symptomatic MGD blepharitis were enrolled, whom treated with BlephEx (Scope Ophthalmics Ltd., UK). Outcome measures were ocular symptoms taken prior to treatment and 1, 3 and 6 months after treatment using SPEED score and OSDI questionnaires. Dry eye disease was evaluated using tear break up time (TBUT). Ancillary treatments were unchanged pre and post treatment. Results: The average SPEED score changed from 16.65 to 6.85 (58% decrease: P<0.05). OSDI score waschanged from 62.50 to 29.25 (53% decrease; P<0.05). The average TBUT improved from 10.1 to 16.8 seconds (66% increase; P<0.05). Two cases of severe blepharo-kerato-conjunctivitis significantly improved. No complication occurred Conclusion: BlephEx is an effective and safe treatment for management of obstructive meibomian glanddysfunction and dry eye syndrome