Longitudinal Evaluation of Corneal Biomechanical Parameters in a 7-11 Year-Old: A Cohort Study
Publish Year: 1397
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
ACSOMED28_130
تاریخ نمایه سازی: 1 دی 1397
Abstract:
Purpose: To determine 4-year changes of corneal biomechanical parameters in Iranian children aged 7-11 years and their determinants. Methods: In this 4-year Prospective cohort study, 468 children aged 7-11 years that were initially evaluated in 2012 were re-evaluated in 2016-2017. Multi-stage stratified cluster sampling was applied. Cycloplegic refraction (Topcon Corporation, Tokyo, Japan), biometry using LENSTAR/Biograph (WaveLight Ag, Erlangen, Germany), and corneal biomechanical assessment using Ocular Response Analyzer (Reichert Ophthalmic Instruments, Buffalo, New York, USA) were done for each subject. Results: All biomechanical parameters except a index decreased in the second phase. The mean changes of CH (corneal hysteresis) and CRF (corneal resistance factor) was 0.68±0.16 mmHg (for both parameters) during four years. The mean difference in CH and CRF was 0.23±0.23 and 0.24±0.23 mmHg in girls and 1.03±0.23 and 0.96±0.23 mmHg in boys, respectively. Different age groups showed varying amounts of decrease in all parameters except for a index. The age group 10 years experienced the smallest change in CH (0.02±0.48 mmHg) and CRF (0.20±0.47 mmHg) and the age group 11 years showed the greatest disparity in CH (1.41±0.35 mmHg) and CRF (0.99±0.34 mmHg). According to linear regression analysis, CH and CRF had a significant direct relationship with corneal power and an inverse relationship with axial length. (P<0.001) Conclusion: Age and sex are determinants of classic ORA parameters. A decreasing trend was noted in the biomechanical parameters in different age groups. Moreover, the decreasing changes in the biomechanical parameters were more noticeable in boys than girls.
Authors
Hamed Momeni-Moghaddam
Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran
Hassan Hashemi
Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran
Mehrnaz Valadkhan
Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran
Nooshin Dadbin
Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran