Prevalence and Risk Factors for Retinopathy of Prematurity in Iran: An Analysis of 1,990 Cases

Publish Year: 1397
نوع سند: مقاله کنفرانسی
زبان: English
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ACSOMED28_181

تاریخ نمایه سازی: 1 دی 1397

Abstract:

Purpose: To evaluate the frequency and risk factors for retinopathy of prematurity (ROP) among Iranian infants.Methods: A retrospective cohort study was conducted on infants seen for ROP screening at the Farabi Eye Hospital, between March 2016 and March 2017. Patients were analyzed based on presence of extreme prematurity (gestational age≤ 28 weeks), extremely low birth weight (≤1000 g) and multiple gestation (MG) pregnancies. Results: The prevalence of ROP was 27.28% (n=543) among all screened infants, 74.4% for extremely preterm infants, 77.5% for extremely low birth weight babies, and 27.25% for infants from multiple gestations pregnancy.On multivariate analysis. Gestational age, birth weight and history of transfusion (p<0.0001, p<0.0001 and p=0.04, respectively) were significantly associated with ROP. ROP presented at more advanced stages (p< 0.0001) in extremely preterm and extremely low birth weight infants. Birth weight (p=0.088), history of transfusion (p=0.066), and intubation (p=0.053) were risk factors for ROP in extremely preterm infants which were not statistical significance while gestational age (p=0.037) and history of transfusion (p=0.040) were significant risk factors for ROP in extremely low birth weight infants. Gestational age (p<0.0001) and birth weight (p=0.001) were significantly associated with ROP in infants from multiple gestation pregnancy on multivariate analysis. Conclusion: ROP remains a commonly encountered disease, especially in extremely low birth weight and extremely pre-term infants. History of transfusion may have a role in stratifying ROP risk and guiding future screening guidelines.

Authors

Mohammad Zarei

Tehran University of Medical Sciences

Fatemeh Bazvand

Tehran University of Medical Sciences

Nazanin Ebrahimiadib

Tehran University of Medical Sciences

Ramak Roohipoor

Tehran University of Medical Sciences