Adrenal myelolipoma: a case report

Publish Year: 1397
نوع سند: مقاله کنفرانسی
زبان: English
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AFZMED02_016

تاریخ نمایه سازی: 30 دی 1397

Abstract:

Background: Myelolipoma is a tumor like lesion with two distinct elements, including adipose tissue and bone marrow hematopoietic cells. In 1905, for the first time the lesionwas described by Gierke, but the term Myelolipoma was introduced by Obreling in 1929. The tumor has most often been identified in adrenal gland without malignantbehavior or endocrine disturbance symptoms. It usually affects males and females equally in adult life. Radiologic imaging like CT scan or MRI is the most common way ofdetecting myelolipoma in adrenal gland. Myelolipomas account for 3-5% of all primary tumors of adrenals Case report: We report a case of 46-years-old man presented with nonspecific abdominal pain for one year, who had right adrenal mass with fat density detected by radiologic investigation. Histopathological assessment of right adrenalectomy specimen revealed the diagnosis of adrenal myelolipoma.Conclusion: Myelolipoma is a rare benign tumor found in adrenal and less frequent in extra adrenal regions. Reviewing of the past literatures shows an incidence of 0.08 to 0.4%at autopsy. The tumor is typically asymptomatic and hormonally inactive, but large sized masses may cause abdominal or back pain. It is characterized by presence of matureadipose tissue admixed with active bone marrow elements, from all three lineage hematopoietic cells (erythroid, myeloid, and megakaryocytic), but often with markedly increased megakaryocytes.

Authors

Elham Jafari

Assistant professor of pathology and stem cells research center, pathology department, Afzalipour Kerman University of medical sciences, Kerman, Iran

Ali Hadipour

MD, Department of pathology, Kerman University of medical science, Kerman, Iran.

Najmeh sadat Fadaei

MD, Department of pathology, Kerman University of medical science, Kerman, Iran.

Hamid Pakmanesh

MD, Department of urology, Kerman University of medical science, Kerman, Iran.