EFFECT OF 8 WEEKS OF AEROBIC EXERCISE AND SPIRULINA SUPPLEMENT ON HEPATIC INFLAMMATORY INDEXES AND LIPIDS PROFILE, IN OVERWEIGHT AND FAT WOMEN

Background and Aim: The aim of the present study is to assess the effect of aerobic exercise and spirulina supplement on hepatic inflammatory indexes and, in overweight and fat women.Methods: In this experimental study with a pretest-posttest design (with control group), 40 overweight or fat women were randomly categorized in three experimental groups: spirulina supplement group, aerobic exercise group, and spirulina supplement and aerobic exercise combined group). We had also a control group. Aerobic exercise performed for 8 weeks and 3 session in each week (one hour sessions). In the spirulina supplement group, 500mg tablets of spirulina were used three times per day, and 30 minutes before each meal. Control group received capsules containing 500 mg of starch 3 times per day, and 30 minutes before each meal. Levels of lipids profile (HDL-C, LDL-C, Chol, TG) and hepatic enzymes (AST, ALT, ALP) were measured before and after 8 weeks, in fasting condition. Results were analyzed using SPSS version 22. To analyze the data, Co-variance analysis with Bonferrine s post-hoc test were used.Results: Only in aerobic exercise along with spirulina supplement group, a significant difference were seen in the levels of total cholesterol (P=0.003), LDL cholesterol (P=0.046), and BMI index (0.031), in comparison to control group. However, none of groups indicated a significant alteration in hepatic enzymes level. Conclusion: Receiving spirulina supplement along with aerobic exercise, improve serum cholesterol levels. Further studies is needed to assess their effects on hepatic enzymes.